Drugstore Cowboy is a 1989 American crime drama film directed by Gus Van Sant. Matt Dillon stars in the title role, and Kelly Lynch, Heather Graham, and William S. Burroughs are also featured. It was Van Sant's breakthrough picture. The film was very well received critically, being listed on the Top Ten list of both Gene Siskel and Roger Ebert for films released in 1989. was filmed mainly around Portland, Oregon, including in an area in the Pearl District.
Xenia, Ohio, is a small poor and boring city that never fully recovered after a tornado in the 1970s. Lonely residents of a tornado-stricken Ohio town wander the deserted landscape trying to fulfill their boring, nihilistic lives. Teenager Solomon and his slightly older friend Tummler, have nothing to do but kill time, buying glue to sniff and get high.